Polyvalent DNA gold nanoparticles - Wikipedia
WEBPolyvalent DNA gold nanoparticles, now more commonly referred to as spherical nucleic acids, (Fig. 1) are colloidal gold particles densely modified with short (typically ~30-mer or less), highly oriented, synthetic DNA strands.
Gold-DNA nanosunflowers for efficient gene silencing with
WEBOct 2, 2019 · Specifically, it is imperative to establish an efficient delivery system for enhanced and controlled gene interference–based therapeutics. Inspired by nature’s ability to hybridize DNA, DNA-mediated self-assembled gold-DNA nanostructures (~200 nm) were designed and fabricated in this work.
DNA-functionalized gold nanoparticles: Modification, …
WEBDec 13, 2022 · Gold nanoparticles (AuNPs) are tiny particles of gold with a size of 1–100 nm ( Cao et al., 2022 ). AuNPs have attracted extensive attention due to their special physical and chemical properties ( Zha et al., 2021 ), which are different from the counterpart bulk materials and small molecules.
A Review on the Synthesis and Functionalization of Gold Nanoparticles ...
WEBDec 7, 2020 · Gold nanoparticles (AuNPs) are an obvious choice for biomedical applications due to their amenability of synthesis, stabilization, and functionalization, low toxicity, and ease of detection.
Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern ...
WEBJan 3, 2020 · Capture DNA strands in the center of the cavity allow the site-specific introduction of single gold nanoparticle (AuNP) seeds carrying DNA strands with the complementary sequence. In the presence of a gold precursor and a reducing agent, the growth of the nanoparticle is initiated.
Clicking DNA to gold nanoparticles: poly-adenine-mediated formation …
WEBJan 30, 2015 · Monovalent DNA–gold nanoparticle (mDNA–AuNP) conjugates hold great promise for widespread applications, especially the construction of well-defined, molecule-like nanosystems.
DNA-Based Gold Nanoparticle Assemblies: From Structure ... - MDPI
WEBNov 16, 2023 · This review first introduces the constructed component types and assembly strategies, including the use of DNA single strands, DNA tiles and DNA origami nanostructures to regulate the assembly of gold nanoparticles into multimers, 1D and 2D arrays and 3D lattice structures.
Gold-DNA nanosunflowers for efficient gene silencing with
WEBOct 2, 2019 · Fortunately, the flourishing field of nanotechnology provides more effective strategies for nucleic acid delivery. Here, the triplex-forming oligonucleotide sequence and its complementary strand were used to mediate self …
Fast microwave heating-based one-step synthesis of DNA and …
WEBFeb 18, 2022 · Here, the authors report a microwave heating-based method for the fast, one-step attachment of a range of thiolated or non-thiolated DNA and RNA to gold nanoparticles.
Gel electrophoresis of gold-DNA nanoconjugates - PubMed
WEBGold-DNA conjugates were investigated in detail by a comprehensive gel electrophoresis study based on 1200 gels. A controlled number of single-stranded DNA of different length was attached specifically via thiol-Au bonds to phosphine-stabilized colloidal gold …
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