Single-cell sequencing - Wikipedia
WEBSingle-cell sequencing examines the nucleic acid sequence information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. [1]
Single-cell sequencing techniques from individual to multiomics ...
WEBSep 15, 2020 · Recently, single-cell sequencing technologies have been rapidly developed for observing the multilayered status of single cells. Single-cell sequencing has the power to elucidate genomic,...
Understanding Single-Cell Sequencing, How It Works and Its …
WEBJan 20, 2022 · What is single-cell sequencing and what is single-cell RNA sequencing? Traditional next-generation sequencing (NGS) examines the genome of a cell population, such as a cell culture , a tissue, an organ or an entire organism.
The technological landscape and applications of single-cell
WEBJun 6, 2023 · Single-cell multi-omics technologies and methods characterize cell states and activities by simultaneously integrating various single-modality omics methods that profile the transcriptome,...
Single‐cell RNA sequencing technologies and applications: A …
WEBMar 29, 2022 · Single‐cell RNA sequencing (scRNA‐seq) technology has become the state‐of‐the‐art approach for unravelling the heterogeneity and complexity of RNA transcripts within individual cells, as well as revealing the composition of different cell types and functions within highly organized tissues/organs/organisms.
Current best practices in single‐cell RNA‐seq analysis: a tutorial
WEBJun 19, 2019 · Here, we detail the steps of a typical single‐cell RNA ‐seq analysis, including pre‐processing (quality control, normalization, data correction, feature selection, and dimensionality reduction) and cell‐ and gene‐level downstream analysis. We formulate current best‐practice recommendations for these …
Single-cell RNA sequencing technologies and bioinformatics …
WEBAug 7, 2018 · Single-cell RNA sequencing (scRNA-seq), for example, can reveal complex and rare cell populations, uncover regulatory relationships between genes, and track the trajectories of distinct cell...
Single-cell RNA sequencing technologies and applications: A …
WEBSingle-cell RNA sequencing (scRNA-seq) technology has become the state-of-the-art approach for unravelling the heterogeneity and complexity of RNA transcripts within individual cells, as well as revealing the composition of different cell types and functions within highly organized tissues/organs/or …
Applications of Single-cell DNA Sequencing - PMC - National …
WEBAug 8, 2021 · Single-cell DNA sequencing (scDNA-seq) encompasses a suite of technologies and approaches that interrogate DNA at the level of single cells. These technologies contrast with standard DNA sequencing, also known as “bulk” sequencing, that homogenizes the DNA content of usually thousands to millions of cells.
The single-cell sequencing: new developments and medical …
WEBJun 26, 2019 · Single-cell sequencing technologies refer to the sequencing of a single-cell genome or transcriptome, so as to obtain genomic, transcriptome or other multi-omics information to reveal cell population differences …
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