Rookie infielder Marcelo Mayer is out indefinitely after suffering a right wrist sprain, which will mean Ceddanne Rafaela — the elite center fielder — playing more second base, manager Alex Cora said Friday.

After Mayer’s injury, the Red Sox recalled infielder David Hamilton, and though Hamilton will see some time at second, Rafaela’s offense has been too valuable to the lineup. Playing him at second and Duran in center makes the offense stronger. The moving parts have been a challenge for manager Alex Cora much of the season and even more so now.