Mutations in superoxide dismutase 1 are a known cause of familial ALS, but does the protein also misbehave in sporadic forms of the disease? A July 23 paper in Proceedings of the National Academy of ...

Protein aggregation is mostly viewed as deleterious and irreversible causing several pathologies. However, reversible protein aggregation has recently emerged as a novel concept for cellular ...

Cataracts account for over half of all cases of blindness worldwide, with the only established treatment involving surgical removal of the opacified lens. In developed nations, cataract surgeries ...

Immobilizing the antibodies on a solid-phase support, such as a resin, and carrying out the conjugation of the payload-linker while the antibodies are bound to that support will prevent aggregation at ...