A 2012 Cochrane systematic review (assessed as up to date September 2011, Nelson et al. 2012) investigated non-surgical therapy for anal fissure. A second systematic review of clinical trials ...
Medical therapy is an established first-line approach for the treatment of patients with chronic anal fissure; however, the efficacy of individual agents versus placebo remains to be proven in this ...
George S. Speare, M.D. Assistant in surgery, Massachusetts General Hospital. Roy E. Mabrey, M.D. Assistant in surgery, Massachusetts General Hospital. Select the format you want to export the citation ...