CRISPR-Cas9 genome editing exploits the CRISPR-Cas system ... strand breaks induces large DNA deletions at frequencies 20-fold higher than elicited by base editors and prime editors leveraging ...

Genome evolution is the process by which a genome changes in structure over time, through mutation, horizontal gene transfer, and sexual reproduction. The study of genome evolution involves ...

Mobile genetic elements, pieces of genetic material capable of moving within a genome, gained the ability ... of the nucleus a complex DNA virus? Journal of Molecular Evolution 53, 251–256 ...

For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but ...

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But because each Nature journal has to decline many papers of very high quality, an editor may suggest that a paper declined for editorial (not technical) reasons may be suitable for submission to ...

The genome is the full genetic complement of an organism, encoded in either DNA or, in many viruses, RNA. It includes both the genes and non-coding sequences.

ReChb can target any nucleic acid, with minimal restrictions, making it a multipurpose tool for genome editing and genetic diagnostics. Optimized methods for the synthesis of circular RNA in vitro ...

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Pangenome graphs signify a new frontier in genome representation. Recent advances in constructing and personalizing them mark progress in this area. In the first-ever Undiagnosed Hackathon ...