Dane -- who shot to fame amid six seasons on the hit ABC drama "Grey's Anatomy," where he played Dr. Mark Sloan, affectionately known as "McSteamy" -- said his symptoms began over one year ago, when he began to experience weakness in his right hand.

Eric Dane — who revealed in April that he was diagnosed with ALS — shared that despite his “setbacks,” he has no plans of giving up his acting career.

Dane is set to share intimate details about his diagnosis in a new "Good Morning America" interview with Diane Sawyer.