An Avon family seeks answers from the FDA after their 10-year-old nearly died from E. coli. The source of the outbreak remains unclear.

A person is dead Saturday after being ejected from their vehicle in a two-vehicle crash on the city's west side.

Firefighters with the Indianapolis Fire Department on Saturday are battling a house fire on the city's south side.

Pascal Siakam scored 21 points, and Myles Turner added 18 points and 11 rebounds to help the Indiana Pacers beat the Philadelphia 76ers.

An Indianapolis man was sentenced Saturday to 13 years in federal prison for drug and gun crimes, including possession of a murder weapon.

Indianapolis Metropolitan Police Department reports a fatal crash on southside. The driver was pronounced dead at the scene.

Woman found dead from trauma injuries in Indianapolis home. Police detain person of interest. More details to follow.

Tenant advocacy groups, landlord associations and elected officials are condemning rent gouging after thousands were displaced in fires.

One of the key questions for the College Football Playoff national championship: Will Notre Dame play man defense against Smith and Egbuka?

EUGENE, Ore. (AP) — Trey Kaufman-Renn had 23 points and 11 rebounds to help lead No. 17 Purdue past No. 13 Oregon 65-58 on ...

Cloudy skies will persist, with flurries or isolated snow showers possible, especially in northern and southern parts of the ...

A doorbell camera on a Canadian home captured rare video and sound of a meteorite striking Earth as it crashed into a couple’s walkway.