Here are 10 factoids about defenders at the NFL combine that could help the 49ers rebound under defensive coordinator Robert ...

A crash involving a big rig on U.S. Highway 101 near South San Francisco caused a fuel spill and knocked out power to ...

Max Darrow reports on South San Francisco officials looking to encourage businesses to fill vacant downtown spaces.

Hillsborough Police seek dash cam footage after an officer was shot on Feb 22; they're intensifying the hunt for a Hispanic ...

The Bulldogs finished the regular season two games under .500 and placed ninth out of 12 teams in the Diablo Athletic League ...

Police in San Francisco on Wednesday announced that the reward for information leading the identification, arrest, and ...

SOUTH SAN FRANCISCO, Calif. (AP) — SOUTH SAN FRANCISCO, Calif. (AP) — Cytokinetics Inc. (CYTK) on Thursday reported a loss of $150 million in its fourth quarter. On a per-share basis, the South San ...

The early morning crash spilled 160 gallons of diesel fuel on the freeway and sent debris into nearby high-voltage power ...

SOUTH SAN FRANCISCO, Calif. (AP) — SOUTH SAN FRANCISCO, Calif. (AP) — Alector Inc. (ALEC) on Wednesday reported a loss of $2.1 million in its fourth quarter. The South San Francisco, California-based ...

SOUTH SAN FRANCISCO, Calif. — SOUTH SAN FRANCISCO, Calif. — Standard BioTools Inc. (LAB) on Wednesday reported a loss of $34.1 million in its fourth quarter. The South San Francisco, California-based ...

Fuel spills and metal beams on Bay Area freeways Thursday morning made for a "ridiculous day," KTVU traffic reporter Sal Castaneda said.