The Sweet 16 round of the 2025 NCAA Men’s Basketball Championship features familiar foes and Southeastern Conference rivals with No. 2 Tennessee battling No. 3 Kentucky.

It’s Tennessee Vols vs Kentucky Wildcats in the March Madness bracket. Here’s our prediction, pick for the 2025 NCAA Tournament basketball game.

Houston, Michigan State and Auburn came up clutch, while Tennessee was a bully from the start in Sweet 16 action Friday night.

Jace Richardson scored 24 points and Michigan State surged past Mississippi in the second half for a 73-70 victory Friday night in the NCAA Tournament Sweet 16.