In this interview, Kalpana Barnes highlights how new approach methodologies are addressing the gaps in drug discovery studies ...

High-Performance Liquid Chromatography (HPLC) is a highly efficient analytical method used to separate, detect, and quantify components within complex mixtures. Based on chromatographic principles, ...

ABSTRACT: A stability-indicating reverse-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the simultaneous quantitative determination of degradation ...

Gas chromatography and HPLC modeling have evolved, providing diverse tools for method development and chromatographic behavior prediction. Empirical DoE and first-principles approaches offer distinct ...

Join host Neil Lander as he sits down with Margaret Maziarz, Principal Scientist at Waters Corporation, to discuss the latest tools and strategic approaches to optimizing method development. Margaret ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. LC-MS and LC-MS/MS (24−27) analytical methods for MK-7 have ...

Background: Ponatinib, a third-generation tyrosine kinase inhibitor, is employed in the management of adult chronic myeloid leukemia. Nevertheless, the presence of process impurities and degradation ...

ABSTRACT: A novel, simple, and sensitive Ultra Performance Liquid Chromatography (UPLC) method was developed and validated for the quantification of process-related impurities and degradants, as well ...

HPLC method development of structurally similar components is an arduous task to undertake. Understanding the principles of liquid chromatography and applying them in a structured, streamlined ...

Abstract: Distributed photovoltaic systems are a recently developed form of distributed power generation that offer the benefits of being both environmentally friendly and highly efficient.As power ...