Buffalo's defense, led by new pass-rusher Nick Bosa, showed the blueprint Sunday to defeating Patrick Mahomes. Will it carry over into the postseason?

With Nick Bosa sidelined, the 49ers are predicted to trade for a four-time Pro Bowler to strengthen the pass rush. The 49ers ...

One player every NFC West team should replace at the trade deadline We all get the same 24 hours. So why should it matter?

The song kind of remains the same for fantasy football owners but a few defenses stand out for the wrong reasons for Week 9 of NFL action.

SANTA CLARA — Remember when training camp began and the 49ers were a star-studded team with high hopes and the NFL’s “easiest” schedule? Fast forward to Week 7. Two of their biggest stars — linebacker ...

The San Francisco 49ers have been hit by injuries arguably harder than any other team in the NFL this season. The team has had several impact players on injured reserve, including tight end George ...

A new report from an NFL insider indicates that the San Francisco 49ers are interested in potentially acquiring Trey Hendrickson.Dianna Russini of The Athletic reports that the 49ers are expected to ...

TAMPA, Fla. (AP) — The San Francisco 49ers lost another key player when All-Pro linebacker Fred Warner left Sunday's loss at Tampa Bay with a season-ending ankle injury. Warner dislocated and broke ...

It doesn't take a football genius to realize that Fred Warner's ankle injury is a massive loss for the 49ers this season. Warner, a four-time All-Pro, arguably is the best middle linebacker in the ...

The San Francisco 49ers were already playing today's game against the Tampa Bay Buccaneers without edge rusher Nick Bosa, who is out for the season with an ACL injury. They'll likely be without ...

Bosa’s ACL tear forces the 49ers to weigh an expensive rental versus internal fixes. Nick Bosa’s ACL injury leaves 49ers without their primary edge rusher Bengals’ Trey Hendrickson emerges as top ...