"Anything can happen in a 1-game sample. But Jacoby Brissett started 5 games and dropped back 188 times for Patriots last season. Brissett completed just 59% of his passes, didn’t throw for more than 168 yards in a game, threw 2 TDs. Only Will Levis was worse in EPA per dropback."

Jonathan Taylor’s one-yard touchdown run gave Indianapolis the lead in the fourth quarter, and the Colts withstood a final drive into the red zone by the visiting Arizona Cardinals with less than a minute left to pull out a 31-27 victory on Sunday and improve to 5-1.

Jacoby Brissett is confident he can lead the offense in place of Kyler Murray if asked to step up for the Cardinals this weekend against the Colts.

Arizona Cardinals tight end Trey McBride was frustrated. For four excruciating weeks, the Cardinals had a chance, and they dropped each one. In this one, a 31-27 setback at Indianapolis on Sunday, the defense was unable to force a punt in the second half,

The Indianapolis Colts rally in the fourth quarter to defeat the Arizona Cardinals. Here are the winners and losers from the NFL Week 6 matchup.