After Demi Moore lost the best actress Oscar to a younger star, Mikey Madison, fans of "The Substance" couldn't help but point out the irony.

Mikey Madison won the best actress Oscar on Sunday for “Anora," a role that catapulted the 25-year-old into a film career after achieving initial success on television. Her victory was part of a huge night for the Brooklyn-set comedy-drama,

The 62-year-old Best Actress nominee who starred in a film about how society prefers younger women lost to a much younger actress.