Experiments in fruit fly larvae show that epidermal cells can communicate with sensory neurons to drive responses to pain.

Phylogeny and spectral sensitivity of ancyromonad ChRs. (A) A maximum-likelihood phylogenetic tree of selected ChRs. The circles show bootstrap support from 40 to 100. (B,C) The photocurrent action ...

This important study describes newly identified light-gated ion channel homologs (channelrhodopsins, ChRs) in several protist species, with a primary focus on the biophysical characterization of ChRs ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. This work by Govorunova et al. identified three naturally ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. In this manuscript, Taujale et al describe an interdisciplinary ...

The authors present an important set of data implicating ETFDH as an epigenetically suppressed gene in cancer with tumor suppressive functions. The evidence is solid, with the authors demonstrating ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In their manuscript, ...

Antibodies that selectively bind distinct amyloid-beta variants are vital tools for Alzheimer's disease research. This valuable manuscript aims to delineate the epitope specificity in a panel of ...