BRAF gene mutations can cause normal cells to become cancerous. Learn about the mutation, the types of cancer it can cause and the treatments available.

Human BRAF genome location and BRAF gene details page in the UCSC Genome Browser. This article incorporates public domain material from Dictionary of Cancer Terms.

Sep 15, 2025 · BRAF mutations are present in many melanomas as well as some lung cancers, colon cancers, and more. Learn about the basics, testing, and treatment.

The BRAF gene provides instructions for making a protein that helps transmit chemical signals from outside the cell to the cell's nucleus. Learn about this gene and related health conditions.

Apr 16, 2024 · In this review, we cover the current understanding of BRAF mutations and associated clinical characteristics in patients with metastatic NSCLC, approved and emerging treatment options, …

BRAF is one type of lung cancer biomarker. BRAF is the name of both a gene and a protein. The BRAF protein helps control cell growth. When there is a mutation in the BRAF gene, it creates an abnormal …

Nov 13, 2025 · BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase) is a Protein Coding gene. Diseases associated with BRAF include Lung Cancer and Cardiofaciocutaneous Syndrome 1. …

With the identification of activating mutations in BRAF across a wide variety of malignancies, substantial effort was placed in designing safe and effective therapeutic strategies to target BRAF.

Dec 24, 2025 · BRAF mutations identify a small subgroup of patients (pts) with non-small cell lung cancer (NSCLC). Dabrafenib/trametinib (D/T) combination is associated with high response rates …

Jul 27, 2025 · BRAF testing detects specific mutations in the BRAF gene that drive cancer growth, which can inform treatment decisions. This test is commonly performed for several cancer types where …