How Dental Caries Develops Dental caries is a chronic, multifactorial disease characterized by the progressive demineralization of tooth hard tissues caused by bacterial activity within dental plaque. 1. Formation of Dental Plaque After food intake, a biofilm forms on the tooth surface, composed of microorganisms—primarily Streptococcus mutans and Lactobacillus species. When oral hygiene is inadequate, this plaque matures and becomes resistant to natural saliva cleansing. 2. Bacterial Metabolism
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